Here, Ellie Lindsay OBE, independent specialist practitioner, associate lecturer, CRICP, London and visiting fellow, Queensland University of Technology, and Laura Talbot, clinical audit consultant for the Lindsay Leg Club Foundation, discuss why effective communication is important in clinical practice to help improve the quality of life for individuals living with a PICC line in situ. This feature also recounts Ellie Lindsay’s own personal experience of watching her husband undergo a period of intense cancer treatment, and the difference made by the communication skills and teamwork of healthcare professionals involved once in the correct haematology unit.