Antimicrobial dressings (AMDs) play an important role in modern wound management. However, their use must be carefully considered to ensure effectiveness while minimising harm. Inappropriate or prolonged use may delay wound healing and contribute to antimicrobial resistance (AMR). Healthcare professionals therefore have a responsibility to use these dressings judiciously, guided by clinical assessment and evidence-based practice. The second part in our new JCN clinical skills series on wound dressings discusses key aspects to consider when using AMDs, while highlighting some of their properties.